Its estimated 3,800 tribal members are resolutely dedicated to sustaining the culture and heritage of their past. Far off the beaten path, 45 minutes south of Clewiston, you’ll find the Big Cypress Reservation, a remote, 82-square-mile tract of land, the largest of six Indian reservations owned by the Seminole Tribe of Florida.Īmong Florida’s tourist destinations, the Big Cypress reservation is unlike any other.